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Definition of Gene amplification

Gene amplification: Making multiple copies of a gene. Repeated copying of a gene.

Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events.

Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=13537
Last Editorial Review: 6/14/2012

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