Definition of Fissure
Fissure: A cleft or groove. A fissure can be normal or abnormal.
A fissure in the cerebral cortex is a normal feature. It is a deep fold that involves the entire thickness of the brain wall.
A fissure in the anus is abnormal. It is a painful crack in the edge of the anus and is very painful. Also called an anal fissure or fissure in ano.Source: MedTerms™ Medical Dictionary
Last Editorial Review: 9/20/2012