Definition of Mental retardation and clasped thumbs
Mental retardation and clasped thumbs: A syndrome with the following characteristic features:
(1) Neurological: Mental retardation and aphasia (lack of speech);
(2) Limbs: Clasped (adducted) thumbs, absent extensor pollicis longus and/or brevis muscles to the thumb, shuffling gait, and leg spasticity;
(3) Skeleton: Lumbar lordosis (swayback);
(4) Growth: Small body size.
The syndrome is inherited as an X-linked recessive trait and so affects almost exclusively boys. Alternative names for the syndrome include MASA syndrome (MASA stands for mental retardation, aphasia, shuffling gait, and adducted thumbs), adducted thumb with mental retardation, congenital clasped thumb with mental retardation, and the Gareis-Mason syndrome.Source: MedTerms™ Medical Dictionary
Last Editorial Review: 6/14/2012
Top RxList Drug News
- First US Case of E coli Resistant to Last-Resort Antibiotic
- FDA Approves Afstyla for Adults, Children With Hemophilia A
- FDA Approves New Diagnostic Imaging Agent to Detect Recurrent Prostate Cancer
- Drug Targeting Blood-Brain Barrier 'Hopeful' in Stroke
- FDA Approves Probuphine Implant for Opioid Dependence
Find out what women really need.