Definition of Roth's spot

Roth's spot: A hemorrhage in the retina with a white center. Originally associated with bacterial endocarditis, Roth's spots may be seen in leukemia, diabetes, collagen-vascular diseases, and other conditions that predispose to hemorrhage in the retina.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=20748
Last Editorial Review: 6/14/2012