July 26, 2016
font size

Definition of Polycystic kidney disease, autosomal dominant

Polycystic kidney disease, autosomal dominant: The most common form of polycystic kidney disease characterized by the progressive development of innumerable cysts in the kidneys, causing hypertension, renal pain, and renal insufficiency (kidney failure). Other features of the disease can be cysts in other organs, such as the liver and 'pancreas, intracranial aneurysms, dilatation (widening) and dissection of the aorta, and abnormalities in the heart valves. The disease is due to mutations in the PKD1 gene on chromosome 16 or, less often, in the PKD2 gene on chromosome 4. Also known as adult polycystic kidney disease.

Source: MedTerms™ Medical Dictionary
Last Editorial Review: 3/19/2012

Drug Medical Dictionary of Terms by Letter

Top RxList Drug News

Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations