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Definition of Anticipation

Anticipation: The progressively earlier appearance and increased severity of a disease from generation to generation. The phenomenon of anticipation was once thought to be an artifact, but a biological basis for it has been discovered in a number of genetic disorders, such as myotonic dystrophy and Huntington disease.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=2279
Last Editorial Review: 3/19/2012

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