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Definition of Antimetabolite

Antimetabolite: A drug that is similar enough to a natural chemical to participate in a normal biochemical reaction in cells but different enough to interfere with the normal division and functions of cells. So named because the drug inhibits a normal metabolic process. Examples of antimetabolites include 6-mercaptopurine (6MP), methotrexate, and hydroxyurea.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=22907
Last Editorial Review: 6/14/2012

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