font size

Definition of EMSY

EMSY: A novel protein that connects the familial and sporadic forms of breast cancer and ovarian cancer.

Some cases of breast and ovarian cancer are familial and strike women in the same family who have a heritable mutation of a gene called BRCA2 that is involved in DNA repair. However, these genetic cases are in the minority. Most cases of breast and ovarian cancer are sporadic. They occur in women with no family history of these cancers.

In sporadic breast and ovarian cancer, EMSY is amplified and overexpressed. EMSY suppresses the activity of the BRCA2 gene. The overlap between sporadic EMSY amplification and familial BRCA2 deletion implicates a BRCA2 pathway in sporadic breast and ovarian cancer. EMSY connects sporadic breast and ovarian cancer to BRCA2.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=25423
Last Editorial Review: 6/14/2012

Drug Medical Dictionary of Terms by Letter

Top RxList Drug News

Women's Health

Find out what women really need.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations