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Definition of CpG island

CpG island: In molecular genetics, a short region of DNA rich in CpG sites, often located near the promoters of genes. Methylation of the CpG sites influences the activity of nearby genes and is critical to the regulation of gene expression.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=26444
Last Editorial Review: 6/14/2012

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