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Definition of Biochemical aspirin resistance

Biochemical aspirin resistance: The inability of aspirin to produce an anticipated effect on one or more tests of platelet function, such as inhibiting the biosynthesis of thromboxane, inhibiting platelet aggregation, and causing a prolongation of the bleeding time. The rationale for this testing is the concern as to whether aspirin therapy can in a given patient help prevent a heart attack or stroke.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=33670
Last Editorial Review: 6/14/2012

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