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Definition of Buprenorphine

Buprenorphine: A prescription medication for people addicted to heroin or other opiates that acts by relieving the symptoms of opiate withdrawal such as agitation, nausea and insomnia. Buprenorphine is more weakly addictive and has a lower risk of overdose than methadone. The effects last for about three days.

Buprenorphine is sold under the brand name of Subutex and, in combination with naloxone, as Suboxone. Subutex is intended for use at the beginning of treatment while Suboxone is intended for the maintenance treatment of opiate addiction. (Naloxone was added to guard against intravenous abuse of buprenorphine by individuals physically dependent on opiates.)

The side effects of buprenorphine include cold or flu-like symptoms, headaches, sweating, sleeping difficulties, nausea, and mood swings. Buprenorphine can cause dangerously diminished breathing, especially when used in combination with alcohol or other central nervous system depressants.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=38304
Last Editorial Review: 6/14/2012

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