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Definition of Locus minoris resistentiae

Locus minoris resistentiae: Latin meaning a place of less resistance. A locus minoris resistentiae offers little resistance to microorganisms.

For example, a damaged heart valve acts as a locus minoris resistentiae, a place where any bacteria in the bloodstream tend to settle.

The concept of a locus minoris resistentiae is an old one but still a valid, useful way of thinking.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=4192
Last Editorial Review: 6/14/2012

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