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Definition of Lyonization

Lyonization: The inactivation of an X chromosome. One of the two X chromosomes in every cell in a female is randomly inactivated early in embryonic development. Named after geneticist Mary Lyon.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=4227
Last Editorial Review: 6/14/2012

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