Definition of Malignant giant cell tumor

Malignant giant cell tumor: A type of bone tumor that is characterized by massive destruction of bone near the end (epiphysis) of a long bone and causes pain and restricts movement. The most common site of malignant giant cell tumor is the knee. Diagnosis is made by examining a sample of the affected area. Treatment involves excising the affected area, usually followed by chemotherapy or radiation.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=4261
Last Editorial Review: 3/19/2012