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Definition of Monoclonal

Monoclonal: Pertaining to a single clone of cells, a single cell and the progeny of that cell. As opposed to polyclonal.

A monoclonal tumor is one that is derived from a single cell and the progeny of that cell. Monoclonal antibodies are produced by a single clone of cells (hybridoma cells) and therefore are a single type of antibody.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=4424
Last Editorial Review: 3/26/2002

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