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Definition of Nucleotide

Nucleotide: A subunit of DNA or RNA. To form a DNA or RNA molecule, thousands of nucleotides are joined in a long chain.

Each nucleotide is divided into three parts (with apologies to Caesar):

  1. A nitrogenous base (A, G, T, or C in DNA; A, G, U, or C in RNA),
  2. A phosphate molecule, and
  3. A sugar molecule (deoxyribose in DNA and ribose in RNA).

A DNA oligonucleotide is a short piece of DNA composed of relatively few (oligo-) nucleotide bases.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=4596
Last Editorial Review: 7/8/2000

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