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Definition of Pseudomelanosis coli

Pseudomelanosis coli: A benign, reversible condition usually, but not always, associated with long-term use of anthranoid laxatives in which pigment deposition in the lamina propria of the large intestine results in a brown to black discoloration of the mucosa (lining) of the large intestine. Melanosis coli produces no symptoms and is indicative of chronic senna laxative use.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=47670
Last Editorial Review: 9/20/2012

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