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Definition of Polygenic disease

Polygenic disease: A genetic disorder that is caused by the combined action of more than one gene. Examples of polygenic conditions include hypertension, coronary heart disease, and diabetes. Because such disorders depend on the simultaneous presence of several genes, they are not inherited as simply as are single-gene diseases.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=4987
Last Editorial Review: 3/19/2012

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