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Definition of Reverse transcriptase

Reverse transcriptase: The enzyme that permits the human immunodeficiency virus (HIV) and other retroviruses to use their viral RNA as a template to make DNA.

Reverse transcriptase is so-named because it reverses the usual transcription of DNA into RNA and allows RNA to be transcribed into DNA.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=5347
Last Editorial Review: 3/23/2003

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