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Definition of Cox-2

Cox-2: Cyclooxygenase-2, a protein acts as an enzyme and specifically catalyzes (speeds) the production of certain chemical messengers called prostaglandins. Some of these messengers are responsible for promoting inflammation. When Cox-2 activity is blocked, inflammation is reduced. Unlike cox-1, cox-2 is active only at the site of inflammation, not in the stomach.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=7121
Last Editorial Review: 3/3/2004

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