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COX-2 Inhibitors (cont.)

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For what conditions are COX-2 inhibitors used?

COX-2 inhibitors are used for treating conditions that cause inflammation, mild to moderate pain, and fever. Examples include:

Unlike aspirin, also an NSAID, they are not effective for preventing strokes and heart attacks in individuals at high risk for such events.

Are there any differences among the different types of COX-2 inhibitors?

Celecoxib is the only COX-2 inhibitor currently available in the United States. Rofecoxib (Vioxx) and valdecoxib (Bextra) are no longer available because they increased the risk of heart attacks and strokes with long term use. Rofecoxib was discontinued in 2004 and valdecoxib was discontinued in 2005.



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