Definition of Macule

Macule: A circumscribed change in the color of skin that is neither raised nor depressed. Macules are completely flat and can only be appreciated by visual inspection and not by touch. Physicians refer to flat skin spots on the skin as macules, as opposed to papules.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=9504
Last Editorial Review: 3/19/2012