Adderall (Amphetamine, Dextroamphetamine Mixed Salts) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 21, 2012

Adderall

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What are ADHD medications and how do they work?

ADHD medications are drugs used to treat some of the characteristic behaviors associated with attention deficit hyperactivity disorder, including inattention, hyperactivity, and poor impulse control.

Drugs used to treat ADHD target chemicals in the brain known as neurotransmitters. One type of ADHD medication works by increasing levels of the neurotransmitter dopamine. Another type of ADHD drug increases the level of another neurotransmitter, norepinephrine.

ADHD drug treatment should begin only after a specific diagnosis of ADHD has been made. A clinical diagnosis requires that symptoms have persisted for at least six months. There is no blood test or radiological scan that can diagnose ADHD.

Most children with ADHD are diagnosed in preschool or early in elementary school. It's estimated that up to 7%-8% of school-age children in the United States have ADHD. In addition, it may be present ...

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ADDERALL® (amphetamine, dextroamphetamine mixed salts)
(amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate)

AMPHETAMINES HAVE A HIGH POTENTIAL FOR ABUSE. ADMINISTRATION OF AMPHETAMINES FOR PROLONGED PERIODS OF TIME MAY LEAD TO DRUG DEPENDENCE AND MUST BE AVOIDED. PARTICULAR ATTENTION SHOULD BE PAID TO THE POSSIBILITY OF SUBJECTS OBTAINING AMPHETAMINES FOR NON-THERAPEUTIC USE OR DISTRIBUTION TO OTHERS, AND THE DRUGS SHOULD BE PRESCRIBED OR DISPENSED SPARINGLY.

MISUSE OF AMPHETAMINE MAY CAUSE SUDDEN DEATH AND SERIOUS CARDIOVASCULAR ADVERSE EVENTS.

DRUG DESCRIPTION

A single-entity amphetamine product combining the neutral sulfate salts of dextroamphetamine and amphetamine, with the dextro isomer of amphetamine saccharate and d, l-amphetamine aspartate monohydrate.

EACH TABLET CONTAINS:	5 mg	7.5 mg	10 mg	12.5 mg	15 mg	20 mg	30 mg
Dextroamphetamine Saccharate	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Amphetamine Aspartate Monohydrate	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Dextroamphetamine Sulfate USP	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Amphetamine Sulfate USP	1.25 mg	1.875 mg	2.5 mg	3.125 mg	3.75 mg	5 mg	7.5 mg
Total amphetamine base equivalence	3.13 mg	4.7 mg	6.3 mg	7.8 mg	9.4 mg	12.6 mg	18.8 mg

Inactive Ingredients:

LACTITOL, MICROCRYSTALLINE CELLULOSE, COLLOIDAL SILICON DIOXIDE, MAGNESIUM STEARATE, AND OTHER INGREDIENTS.

Colors:

ADDERALL® (amphetamine, dextroamphetamine mixed salts) 5 MG IS A WHITE TO OFF-WHITE TABLET, WHICH CONTAINS NO COLOR ADDITIVES.
ADDERALL® (amphetamine, dextroamphetamine mixed salts) 7.5 MG AND 10 MG CONTAIN FD & C BLUE #1.
ADDERALL® (amphetamine, dextroamphetamine mixed salts) 12.5 MG, 15 MG, 20 MG AND 30 MG CONTAIN FD & C YELLOW #6 AS A COLOR ADDITIVE.

What are the possible side effects of amphetamine and dextroamphetamine (Adderall, Adderall XR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using amphetamine and dextroamphetamine and call your doctor at once if you have any of these serious side effects:

fast, pounding, or uneven heartbeats;
feeling light-headed, fainting;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);...

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What are the precautions when taking amphetamine, dextroamphetamine mixed salts (Adderall)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to sympathomimetic drugs (e.g., epinephrine, pseudoephedrine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain mental/mood conditions (e.g., agitation, psychosis), heart/blood vessel disease (e.g., irregular heartbeat, coronary artery disease, angina, heart failure, cardiomyopathy), problems with heart structure (e.g., valve problems), history of heart attack or stroke, moderate or severe high blood...

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Last reviewed on RxList: 10/4/2010
This monograph has been modified to include the generic and brand name in many instances.