The one side effect that I hate is that over the years (almost immediately, and continuingly) I gained 50 lbs.--wasn't eating even 1/3 of what I used to eat. When it says in the side effects "may cause weight gain" it REALLY DOES, and I haven't been able to lose that weight. Published: October 29, 2007 ::

In about 6 months with Actos I have gained 15 pounds. I had been able to control my glucose level for nearly 6 years with diet and exercise before my levels increased. Actos gives me a range of readings from 94 to 140. I am eating less and exercising more than ever to NO avail. Additionally, I have had about a dozen days of low blood sugar. I would gladly go to something else if there is something better. I have given Actos a fair trial and am very disappointed. Does the maker NOT understand Type 2 diabetes at ALL? Weight gain as a side effect is ludicrous! Dr. Walter Yingling Published: October 16, 2007 ::

In two years taking actos not only I gained 25 pounds, but I also retaining water and having hard time to breath with swallon ankle and hands. I got off and not going back even if I die. I am seeking another med. Published: October 26, 2007 ::

sugar level droped from 120 to 108, but i gaind 20 pounds in two months need to get off actos Published: October 21, 2007 ::

Actos helped me to smooth my glucose levels and to stay within normal ranges. I had some difficulties at first with gastrointestinal distress but after several months I was able to figure out how to manage by eating the right things. Published: September 18, 2007 ::

I asked my Doc to talk me off Avandia because of FDA warnings; started Actos a few weeks ago. I have defintely gained weight already and started having diffuse pain in my thighs. So I called an on-call Doc and he said to stop it and talk to my regular doctor. I did, and after a week, my pants started falling off me...seriously...and the thigh pain went away (it had been feeling like I had been doing heavy weights/leg extensions in the gym). So, then my regular doc finally go ahold of me and said to start it this weekend again, and if I started having problems, he'd switch me back to Avandia. Well, in just 2 days I can already feel a little pain in my thighs and I feel like my pep is being zapped. I'll call him tomorrow and switch back and take my chances with Avandia, which I had no problems with in the first place. Published: February 10, 2008 ::

i have just been placed on actos,but in reading the downside where there ig tooth problems and water retension.the tooth problem in what way is this a problem and is there another medication to take with much less downside.i also take glocavance too Published: September 24, 2007 ::

This drug gave my husband congestive heart failure please watch you feet and legs swelling my husband has been in the hospital twice in a month and they found out it was the drug that was causing it Published: June 22, 2008 ::

I have been taking this medication for about a year and have experience swollen ankles, stiff fingers, tooth problems I didn't have before, weight gain of over 50 lbs that I can lose no matter how hard I try, muscle aches and breathing problems. My doctor put me on this medication because my sugar levels jumped to 200 after meals. I also take glipizide. I'm going to stop taking Actos for a couple of months and see if my problems disappear. If they do, then I'll stop taking the medicine completely. I'm tired of the mucles aches that cause me to be too tired to do any of the activities I enjoy doing. Published: April 11, 2008 ::

Takes all energy away. can hardley move about. Dont want to get out of chair. Very dizzy anytime anywhere. Published: October 06, 2007 ::