I have had major depression all my life, and been on every drug. EMSAM has alleviated a great deal of the depression--and that is truly amazing. My energy level is way up from previously. I responded very quickly to 6mg. I have not had any skin irritation at the patch site. I alternate arms each day. I have also lost weight! I'm pleased that I don't have to be too concerned about the dietary restriction at 6mg. I have however developed trouble sleeping and started taking Ambien. The worst problem is a terrible restlessness that even yoga, exercise and meditation won't relieve. I even have stress rashes on the backs of my hands. I'm hoping to be able to manage this because the anti-depressive response has been so remarkable--when so little else has helped. Published: April 24, 2008 ::

Initially I started on the 6mg. patch, raised to 9mg. after 1 month. I showed improvement after 2nd month. Some side effects are swelling in hands, slight rashs, tingling in feet and buzzing in head, some ringing in ears. Depression was severe and now mood has improved significantly. Hopefully, I will not experience any urinary retention like I have with Nardil after a six month period forcing me to discontinue that MAOI.My psychiatrist is going to try alternating between a 6mg. & a 9mg. patch on a every other day basis. My fingers are crossed that it may lessen these side effects and I will be able to stay on this medication for a long time. Published: November 28, 2007 ::

Emsam has worked where all other antidepressents have failed - 9mg. I've been down the whole list. One side effect has been an allergic reaction at the point of application. Local itching and redness under the patch and if left for the prescribed 24 hour period - blistering and skin seperation. I need the medication so I do the following. I move the patch to a new location - tape it down with paper tape - every six hours and then only use it twelve hours a day. Selegiline has a half life of three hours so I'm able to sleep eight of the twelve hours I'm not useing the patch. A patch will last me two days. Even then I have minor skin damage that takes several weeks to heal. But I have lots of skin area and just keep moving it around then I can come back and reuse a previously used area. The Emsam/Selegiline medication has saved my life. I would like to hear from others that might have experienced the same reaction. Published: March 26, 2008 ::

Started 6mg went to 9. Still waiting for it to work. Helps anxiety. Depression still exists. Sticks best to upper thigh. I would like to see it work better/faster for depression. Published: November 08, 2007 ::

problems with constapation, Night sweats, no sexual intrest. dark urine stinks Published: October 09, 2007 ::

I have been on the emsam patch for a year now and I have had less episodes of crying and feeling depressed am experiencing high levels of anxiety right now.For anyone who is having a hard time keeping the patch on I have found that cleaning the area with rubbing alchohol first and then applying benzoin tencture compound then putting the patch on it will not come off till you take it off.It works very well. Published: August 06, 2008 ::

Skin reaction as to where the patch is placed on the skin. The skin is damaged to the point of bleending. It taked two weeks for the spot to heal even with treatment with a rash cream..I run out of placed to apply it. It is very costly $438.00 for 30 day supply. Insurance not covering it at this time.The medication is an old medicine but Drug Company is taking advantage it being a patch. I question its value (treatment vs cost)There has to be a better way. Published: October 22, 2007 ::

The patches leave redmarks that last for well over a week, I look like I have huge polk a dots all over where I have applied the patch. They also dont stay on very well. I feel like I could bust out crying, but really never do. Just not feeling very happy on this drug. This is my second month on it, about my 6th week. I will give it another month and see if I feel better. I went on it because prozac kills your sex drive, this drug does not, thats the upside. Published: September 22, 2007 ::