I can't really judge its effectivness since after two months of it I had to discontinue it. The side effects were horrible! My mind was fuzzy and I was exhausted from lack of sleep. Between the night sweats and waking up every 1-2 hours with severe hip pain what sleep I got was fitful at best. I immediately gained weight had joint and muscle pain that nothing could ease. Hot and cold flashes were plaguing me day and night as if my internal thermostat was bad. The list of side effects is quite long so I will give you the abridged version. To name a few: breast pain, headache, backache, blurry vision, shortness of breath, nausea, stomach pains, etc. The final straw was when I got up from bed, about two steps toward the bathroom, I went blind. It was like someone flipped a switch! There was no lightheadedness, just no vision! After a few seconds and lots of blinking my vision returned. My MD says that the Femara probably caused my blood pressure to fall very low while I was asleep, causing the blindness. If it dropped that low, I would think I am lucky not to have had a heart attack or stroke. I give up. I now intend to try through diet and exercise to keep the cancer at bay. Make sure you are monitored very closely when taking this medication!!! I can't stress that enough. Arimadex was just as awful for me and I had to quit that one, too. I have been on these drugs since around April of this year, but no more!!!! Published: August 30, 2008 ::

I have arthritis, bone pain, joint pain,hot flashes, night sweats, can't sleep,blurred vision, inflamed eyes, never feel good, always tried, I worry I will end up in wheel chair, This has be be one of the worst drugs I've ever taken, to stop cancer they kill the rest of you, what kind of life do I really have? And still this cancer can come still come back, what the Hell, maybe better off taking my chances without this drug. My menory is going and what else do we have? Published: March 24, 2008 ::

Started this after 3 and a half years on tamoxifen (no picnic but tolerable), then 6 months of Arimidex with swollen, tingly and painful hands and feet, puffy face, joint aches, interrupted sleep, crazy moodiness. Switched to Femara for 2 months hoping to diminish side effects (which didn't happen) and night sweats and coordination worsened. Fell twice in two days, with bad bruising, and decided to stop the medication. Oncologist told me to take a break and then start Aromasin after I recovered, but it has now been 5 weeks and the pain and swelling are still present. It seems the effects of the medications have been cumulative over 4 years. Has anyone out there experienced this and recovered, or is the damage permanent? Oncologist said he sees maybe 3 or 4 patients a year (out of hundreds treated) who have this kind of reaction to aromatase inhibitors, but judging by the ratings here it appears more common. Published: January 06, 2008 ::

I have taken this drug for 3 years. I have lost 20 pounds in the past 6 months and I am still the young 44 year old that I should be. I have hot flashes, some insomnia and get muscle cramps in my lower legs and feet, but they are not major problems. As for sleep, I just wear myself out (working or shopping) and then I can get a good nights sleep. Published: January 30, 2008 ::

Aches, pains, minor arthritis type symptoms. Published: September 18, 2007 ::

Bone loss, elevated cholesterol, joint pain and lower back pain, fatigue, insomnia, night sweats and weight gain. Mobility that of someone much older. One year and it is working so far. Quality of life definitely affected, however. Published: January 30, 2008 ::

Since starting on Femara 1 year ago, I seem to have begun having cylical symptoms, i.e., night sweats, excessive sweating with exersion, mood swings, sleeplessness, increased anxiety, and other PMS type things. I had been post-menapause for 5 years before the breast cancer was diagnosed. I am also continuing to fight the fatigue. Published: October 10, 2007 ::

Have much joint and muscle pain- take aspirins 2-3 times a day; also have hot flashes, cholesterol went up so now on Lipitor and hair has thinned a lot. Bone density shows close to osteoperosis. Headaches are daily-sometimes w/ dizziness; very depressing. Wish there was a better alternative med. Almost been 5 years. Published: February 20, 2008 ::