Doctor told me that if the hyalgan did not work my only alternative was knee replacement. Received the series of 3 injections in May and I had no issues with pain from, during or after the injection. While I stll hear a lot of the noise from the knee (popping and grinding), there has been little pain and no swelling since then so this treatment has really made a huge difference. It is now September and I am starting to see some of the pain slowly start to return - but the treatment was only suppose to last 6 months so that's to be expected. Overall my experience with this medication has been excellent.

After undergoing arthroscopy surgery to repair torn meniscus, pain in knee was worse than prior to surgery. Doctor attributed pain to progressive arthritis. Underwent 5 injection series in December 2010. Have only experienced slight improvement. Knee flexibility has improved slightly and pain has been slightly reduced. I still have a hard time climbing stairs and walking without a severe limp. In summary this treatment was not very effective in my case.

I received three injections over the course of 6 weeks at the VA. Injections were painful for several days afterwards. After the third injection I began having having severe pain and swelling in the left knee joint. Gross swelling appeared above the knee to the size of a football from a possible leak in knee tissue/surrounding membrane. Subsequent MRI revealed a tear in the menismous in the left knee. I endured 2 very painful aspirations of the left knee procedures, with nearly 1 liter of fluid taken off the first time and nearly 2 liters of fluid removed the second treatment. I am now scheduled for a total knee replacement in May.

Has gave some relief from a surgery. Injections painful and caused bruising. did cause a significant amount of stomach distress,burning about hour after injections,and mild upset during the five weekly injections. not so sure the painful shots were worth the minor improvement.

I had the series of 5 injections of this. I now have worse pain in my knees than ever before. Plus getting the injections hurt terribly. I wouldn't reccomend this.

After the first series of 3 shots, my knee did feel somewhat better. I seemed to have a wider mobility base then before the shots. After about a month, the feeling better quickly wore off. I have been receiving the shots on a bi-annual basis but the time of better feeling after the shots is about a week. After 5 sets, my doctor told me that it is time for a knee replacement.