I have debilitating fibromyalgia and some arthritis. I was unable to work for months and was wondering what my future held. I started taking Limbrel and the pain is about 95% gone. It also helps with the fatigue (pain causes fatigue, I believe). Just wish they would work with the insurance companies to get it covered. It's been a miracle for me!

After three months of severe pain in my hands for which the orthopedist prescribed steroids followed by NSAIDS (my pain continued with higher and lower intensity throughout the three months of treatment), I decided to see a rheumatologist. He prescribed Limbrel. It is definitely a miracle drug and my pain went from a severe 10 to no pain within 48 hours. The first day I took the medication my stomach was very upset, however, within 3 days the stomach pains decreased and by the fourth day, I felt perfect. I have been taking Limbrel for a month, I have no stomach issues, no pain in my hands and I work in front of a computer, typing, an average of 12 to 14 hours a day.

I've been taking 500 mg of Limbrel 2x daily for 3 months and it works well; more flexibility, less knots and less pain-helps moderately with the fatigue. I have had Fibromylagia for 15 years and NSAIDS have caused all types of stomach problems. My MD informed me today that there is a new program to help with the affordability of Limbrel. $60.00 per month for the prescription if purchased through a www.designrx.net (mail order or walk-in). I am so glad that the tis program is available for all of us who can't afford the $160 per month charge.

First of all, I am a very healthy person that happens to have osteoarthritis as a function of my age. After a certain time using Limbrel I developed an unexplainable fever accompanied by chills,body aches,nausea,and fatigue. I had to be hospitalized for 4 days and received 3 units of blood for extreme anemia. The anemia could not be explained, neither could the blood in my stool. After an upper and lower GI work-up nothing significant could be found to explain the blood loss. People should be aware that Limbrel can cause all these side effects. I am 100% better after discontinuing the drug. The slight improvement I found to my osteoarthritis is not worth the terrible way Limbrel made me feel in general.

Seemed to help almost immediately. One deterent is that it is not available in a generic form--hence, it is pretty costly.

I began taking this medication about 6:00 p.m. All was well until about 2:00 in the morning. I began violent diahrrea that lasted until approximately noon the following day. It was as if I was prepping for a colonoscopy. The entire day I was sluggish, queasy and basically just lethargic. I will not be taking any more of this medication. Have a sixty day supply minus one.

This seemed to help for the first few days. However, I experienced flu-like symptoms, joint and muscular pain (where it had not been previously) and generally felt ill. Fortunately, it occurred to me that it might be the new medicine. After discontinuing Limbrel for 5 days, I am feeling better but not back to pre-treatment health.

I have a torn ACL and leaking Baker's cyst. Limbrel has worked well at reducing the inflamation and pain, but unfortunately, the diarrhea is not tolerable for me long-term. I haven't noticed any other side effects.

I did a Google search for Limbrel reviews & found these 58 WebMD reviews which have been a GODSEND! I've been on Limbrel for about 4 months, prescribed by my Pain Mgmt doc for severe OA of the entire spine, hips, hands and feet (at the ripe old age of 52). All was ok until about 3 wks ago when I suddenly became very sick, vomited 2x, extreme ongoing nausea, stomach pains that resembled my bout with Norwalk Virus and/or when I had an ulcer + on/off bouts w/intestinal issues. I've tried Tagamet, Tums, Pepcid AC & Acidophilus daily but still have stomach pains + unlike the ulcer I've also been achy like the flu, running a low grade fever for the entire 3 wks, and can barely function during the day. When I got blood test results back from family doc my liver GGT count was way off + I was ANEMIC, so my doc corned me w/ possible alcoholism. On my end I kept thinking I had picked up something from the nursing home where I visit my father, but nurses said nothing similar was circulating. It's been VERY frustrating since I have 2 1/2 acres of rescued animals to care for daily and my husband has had to pick up the slack daily while I lay on the sofa + the animals keep coming up to me like something is wrong, checking to see if I'm OK since I'm normally very energetic and caring. I was pretty aggravated at Humana for not covering my Limbrel and I've been paying over $100 per month for this "FDA approved drug", only now to discover that it might be the source for my feeling HORRIBLE for so many weeks! After reading all of tonights online research I do believe that I'm suffering from Limbrel toxidity. Heck I had started telling people I thought my husband might be poisoning me! I never did pin point Limbrel as being very helpful w/pain mgmt since I also take Tramadol (Ultram) & Zyflamend (herbal anti-inflammatory). But after tonights reading I will certainly NOT take it tomorrow and see if I feel better! Thanks a MILLION to those who wrote reviews~ I'll try to post an update.