I took 2 three month injections for endometrosis. I had severe headaches and abdominal pain. When the injection wore off at the end of my last shot, I had severe headaches, dizzyness, hot flashes, mood swings, and fatigue. Published: October 26, 2007 ::

I have severe endometriosis and had two shots of the lupron. It worked for the pelvic pain well enough after the first shot. I had lots of hot flashes and mood swings. When the firs shot started to wear off i started to get migraines really bad. After the second shot, my pain came back full throttle. Published: September 21, 2007 ::

This medication had horrible side effects. The hot flashes are very uncomfortable. Also my muscles, joints, and bones have been horribly effected, to the point where I am on long term pain medications. I am also having to limit my physical activites, like having a good work - out at the gym. My last work out session caused me to get a sprain in my general shoulder area, this has happened twice. Published: February 06, 2008 ::

The side effects can be rough in the beginning, but there are ways to help. Add back therapy has worked wonders for me :) Hot and cold flashes are very slim and other side effects are nonexistant. I highly recommend this drug to anyone who is suffering from endometriosis! I am only 25 and have been living with endometriosis for 10 years, and believe me the shot is worth it! Before Lupron I had 5 laproscopic surgeries for cyst removal, and 1 surgery that resulted in the loss of an ovary, tube, and 25% of my colon.. So, to me its absolutely worth it. But, talk to your doctor about ALL SIDE EFFECTS and PRECAUTIONS while on this drug. My doctor and I discussed Lupron for months before I made my decision. And too often, we let our doctors give us drugs that we don't know what they are for and how to properly use them. Do not be this way about just Lupron, use common sense everytime they write you a prescription! And do research as well. A lot of people on here blame their doctors when the only real person they can blame is themself. Published: July 17, 2008 ::

There are side effects that you should discuss with doctor. For prostate treatment, I understand "flare" can be reduced be preceding treatment with Casodex. I had pain around site of 2nd injection, which went away after a few days. Fatigue is main side effect now. Published: December 02, 2007 ::

I started this medication for endometrosis, I had hot flashes as well. the side effects wernt so bad but it has been almost a year and my cycle hasn't came back. Is this normal? Published: October 27, 2007 ::

Took it for Endometriosis I feel this Medication possibly gave me a stroke. Stay away from it. Published: October 20, 2007 ::

I am 25. I was diagnosed with moderate/severe endrometreosis after undergoing exploratory surgery for my abdominal pain. I have been using Lupron for about 7 months. I do have excessive hot flashes, mood swings, and lowered sex drive, just like during menopause. I was prepared for all the side effects because of my doctor. And I would have to say that the temporary side effects are better for me than what I was experiencing (the sudden crippling pain, pain during sex, and worst of all the possibilty that I might not be able to have children.) I am however looking forward to when the hot flashes, mood swings, and lowered sex drive will stop, and I am sure my husband is as well. Published: March 19, 2008 ::

TERRIBLE SIDE EFFECTS_ DO NOT TAKE Published: November 02, 2007 ::

I took one dose of Lupron for endometriosis, and it not only excaserbated my condition, but severely messed up my mood. I had a mildly heavy period for the whole three months, horrible cramps (worse than when I was off it), and it relapsed my depression. I told my doctor I had mood issues, and he assured me Lupron would not affect my mood. Boy was he wrong: I fell into one of my deepest depressions to date, becoming listless, hopeless, and suicidal--I almost got hospitalized twice while on it. Three days after my dose wore off and I switched to a new medication, my period and cramps stopped (well, mostly) and my depression cleared. IF YOU HAVE ANY HISTORY OF DEPRESSION, ANXIETY, OR OTHER MENTAL HEALTH CONDITIONS, BE EXTREMELY CAREFUL TAKING LUPRON!!! Published: January 04, 2008 ::