My mother in law injects me once a day for a 5 day run each cycle of chemotherapy. The injection doesn't hurt much at all. I didn't have any side effects until my 5th shot. I have experienced pulsating pain in my lower spine and some other bones. Nothing a Tylenol can't take care of. Also I had a headache (but not sure if that is related or not). Overall, piece of cake.

got the shot on Tuesday. Saturday up all night with pulsating pain in lower back both sides. Pain increased upon urination and defecation. Lasted partly thru Sunday.

I have taken 480mcg (the higher dose, there's a 300mcg dose too) for three sessions now - they brought my neutrophils, white blood cell count and hematocrit all up - really well! I had one evening of pulsing pain starting from lower back - real misery, but got permission to take ibuprofen and even just 400mg of that knocked the pain out. Have also had extreme pain on defecation once. Aside from these two, and only one lasted a few hours, all subsequent treatments have not really increased joint pain much. They *have* increased nausea/acid/gas, but meds help that. Just keep on the ondonsatron and you'll be ok.

hurts initially when injected. pain goes away very quickly. suffer fron muscle and bone ache constantly

Had life threatening allergic reaction to Neupogen.

helps in recovery during chemo. blood count bottoms out a week after treatment but with the meds it stabalizes a couple of days later. Very effective.

I have experienced joint pains while on neupogen but for the most part it was tolerable.

I have to take shots everyday, I have been on it daily at a lower dosage for about 4 months now, and I have now developed a great deal of pain in my kidneys and have started bruising so easily. It has stabilized my counts so that I am not getting sick as often. It did not really help when I took the larger doses 3 times a week. It was also difficult to get my insurance to cover the RX for me to take it myself at home.

Being treated for Breast Cancer, I'm on my 4th month of chemo. Taxotere is followed by 2 days of Neupogen shots. I've had no ill side effects, and go to the oncologist for the injecttion. It stings a lot, but pain goes away.

decrease in neutrophils in wbc, due to ribovarrin therapy and pegininteronalpha2a injections.

The only part of this Drug that I found to be unsatisfactory is the joint pain.