Pain in the feet and the legs combine with the headaches has made this drug an evil necessity. Published: October 21, 2007 ::

I actually have had very few problems with Prograf in almost 8 years until a recent dip in my liver & prograft levels that resulted in a higher dose for a few weeks. I started severe headaches several weeks ago that will not go away and have constant nausea so bad I can hardly eat. I do have to take a sleeping pill at night because of insomnia I think is caused by the Prograf. All in all, I feel that I have done very well and have been lucky not to have had some of the bad side effects I have heard others talk about. Published: January 06, 2008 ::

I don't like the it because I am now a diabetic and have high blood pressure because of taking this medication, But it has kept me from rejecting my liver for 11 years now. Published: September 21, 2007 ::

I've suffered serious headaches as a result of this medication, in the form of tension headaches. Unfortunately, muscle relaxers don't work for me (because of other auto-immune diseases), so sleeping them off is my only option. Also, major changes in the dose of this medication cause me to have flu-like symptoms for two to three days after the change. Published: December 02, 2007 ::

I'm satisfied because I haven't rejected (8 yrs and counting) but I did have absolutely the most horrifying nightmare the first time I used it (as I was warned to expect). After that no nightmares, but I have not been able to sleep since (I'm not a wuss - it's not because I fear another nightmare - that was a one time event -- but more because it happens to be one of the side effects.) I take one half milligram of Xanax at night and sleep well and wake up easily and rested. Bottom line.....it beats dying. Published: April 12, 2008 ::

Took this medicine 5 years caused multifocal leucoencephalophaty and now I am confined to a wheelchair. Worked good while I took it, but side effects terrible. Published: March 15, 2008 ::

After four years on this drug, I have had no rejection episodes. I have developed diabetes (but could be from prednisone). I take Reglan for nausea. My docs have been able to reduce my dose easily so my levels are relatively low. Published: February 08, 2008 ::

the drug manufacturers don't tell us about hair loss, brain damage, severe depression, hallucinations, spinal cord damage, memory loss, cognitive problems, shaking, etc. I've been on it for 5 years and my pre-prograf MRI of my brain was fine. Now I have brain damage. I've also been diagnosed as severely bi-polar, and my once thick hair is all but gone! Published: January 12, 2009 ::

the medication is okay, but it gave me alopecia. was not listed as side effect. Published: December 10, 2007 ::

Feb. 19th '09 will be 1 year since Liver Tx due to Cirrhosis caused by Hep-C. Also development of liver Cancer. Initially I was taking 3.5mg twice daily, increased to 4mg daily, gradually reduced dosage until now I am at .5mg(1/2mg.) daily. Blood work shows Prograf level at 6.4-6.9. Type 2 Diabetes was controlled by diet prior to Tx. Now must use insulin. Very happy with results. Also taking Ursodiol, Magnesium supplement, Mega-Vitamin supplent. Published: January 30, 2009 ::