Here is a collection of user reviews for the medication Rocephin sorted by most helpful. 
The following Patient Discussions have not been medically reviewed. See additional information.
it gave excellant effect and no side effects at all when given diluted over 200 cc saline but with the 9th day just after the injection my son eveloped rigors thenafter few hours red rash over his body followed after one day with calf muscles pain Published: October 15, 2007 ::
I was also diagnoses about 3 years prior to Lyme with MS. I am GRAVELY allergic to Rocephin but was forced into the ICU for desinsitization to the drug since it was my only treatment option(allergic Penecillin too). So far desensitization seems successful, though initial 48 hours in ICU were a little rough. 2 weeks into another 4 weeks of treatment and the swollen Lyme arthritic knees are healing and I can walk again without tremendous pain. So far so good. Just wanted to share my apparent success with temporarily disarming my ROcephin allergy with my immunologist, and a fleet of doctors and nurses to get the treatment I needed desperately. Published: May 02, 2009 ::
this drug can cause a reaction of nevousness, tingling, rage. Published: October 28, 2007 ::
I had to have a IV 3 times with this stuff due to a bad skin infection that turned the skin around it to cellulitis. Please be carfull this drug it gave me C. difficile (a severe infection of the colon). You think i would have learned after the first time but no i did it again. Now i have a sensitivity to alot of antibiotics not fun with cronic skin infections. Published: January 25, 2008 ::
I got a severe rash on my arms, hands and legs from this drug given IV. From my knees down it was the worst, large blisters that left scars. It started as tiny red spots on my thighs. No one listened when I told them it could be an allergic reaction, and all the doctors that saw it said they had never seen a Rocephin rash that bad before. Needless to say it's now on my drug allergy list. Published: December 31, 2007 ::
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My husband is in the hospital and is getting this every 24 hrs. I noticed on the 2nd day he has a horrible, raised, red rash. It's all over the upper part of his body (waist up) and on his head. Published: November 20, 2007 ::