Once I added provigil and adjusted dosage this drug was miraculous but before that I had narcolepsy and catalepsy symptoms that would put me on the floor without warning. Be very careful when switching from a dopamine agonist to this drug. It took 4 months to find a solution to the narcolepsy problem and I had to add midodrene to combat orthostatic hypotension for a couple of months. I went from barely functional on dopamine agonists to almost a total invalid initially on sinemet for four months. You must avoid large amounts of food particularly meat for at least 30 minutes, preferably an hour, after you take the drug and two hours before or your symptoms will come back in full force which is not fun. It is well worth switching. I am basically normal now when the medication is working after 8 years of fairly severe symptoms. I also don't take any sinemet during the night. Last CR is at 7:30pm and first is at 7:30 am in the morning. I take .5 mg of azilect at night and 1/4 tablet of lowest dose clonazapam to stop acting out dreams. Published: October 25, 2007 ::

Patient experiences serious halucinations. Published: February 17, 2009 ::

I was prescribed this medication for RLS and even though it worked on RLS I could not sleep since the side effect of sleeplessness kept me up! Published: June 23, 2008 ::

I have used this med for RLS about a year now. I began with a low dose at night which helped for some time however at about 9 months of use it began to wain in it's effectiveness. Just recently had dose increased and using a CR dose twice a day. Seems to help with occational breakthrough when I am close to my next dose. Overall satisfied and easy drug to tolerate. Published: October 21, 2007 ::

extreme weakness overall Published: February 09, 2008 ::

i've been on sinemet for 2 months for rls. it worked wonderfully at first but now i am waking every morning at 3 or so with jumpy legs. it seems i may need a higher dose. no side effects noticed. Published: December 16, 2008 ::

Sinemet taken for RLS early in the day makes me sleepy; but not when taken at bedtime. After taking it for 1 year, effect has waned and dose must be increased. For that first year, it worked wonderfully, with no side effects. What a relief from years of RLS misery! Published: September 08, 2008 ::

I was prescribed this drug for RLS. It caused excessive insomnia, inability to concentrate and I saw flashes of lights that were not there. It was a terrible and frightening experiences for me. The Dr. took me off it after 4 weeks and it took another 3 weeks for s/s to get better. Published: November 22, 2008 ::

This medication relieved my RLS the first time I took it...after that...NO RELIEF Published: September 29, 2007 ::

After 4 1/2 years it appears that some side effects have been causing me more problems. Published: March 10, 2009 ::

It seems to slow down the disease.I also take Mirapex Published: December 22, 2008 ::