I was diagnosed 3 years ago with CML, I was put on Gleevec which after one year my body rejected it. I was put on Sprycel 140mg. I was Philiidelphia Chromazone positive with CML. After one year I was reduced to 100 mg, now there is no PH positive in my blood, my leukemia is holding it's own on just 50 mg. I have had no side effects while on this drug like I did with Gleevac. My hair has grown back in, my potassium levels never drop out of the normal range now like it did on the Gleevac. I am extremely satisfied with this drug, and because it's less expensive then the Gleevac, it should be the first offered when first diagnosed. Patient Published: September 05, 2008 ::

In 9/08 I was diagnosed w/ Philadelphia chromosome positive CML. I have a long history of migraines, that, w/ daily medication, have been under control since 2001.When I 1st started Sprycel, I had an almost constant mild migraine (yeah - an oxymoron) for 8 days. On the 9th day no migraine & I've been migraine free since. I've had no other side-effects. At my diagnosis, 88% of the cells in my bone marrow were leukemic. At my last biospy in 12/08, only 6.5% of my bone marrow cells were leukemic. So the Sprycel is working! Published: January 28, 2009 ::

Went into respiratory failure within 7 days of taking this medicine Published: July 16, 2008 ::

My father has been on this for 1 year, has extream weight loss. Continuous fluid in bothlungs requiring draining per aspiration several times and this week,chest tubes. Published: June 24, 2009 ::