Selzentry (Maraviroc) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 27, 2012

Selzentry

HIV and AIDS: Antiretroviral Drugs, Treatments and Medications »

Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist

Entry Inhibitors
Entry inhibitors block HIV entry into CD4+ cells.

Fusion inhibitors
The only drug in this class is T-20, which is administered as a twice daily subcutaneous injection. The most common side effect is redness and pain at the site of injection. Rarely, infection can occur at the injection site. There also are reports of generalized allergic reactions.

CCR5 antagonist
Although there were some early concerns of liver inflammation for drugs in this class, MVC appeared to be well tolerated in clinical trials without any specific toxicities attributable to the drug. However, it is a new drug in a new class and the first to actually target the cell. For these reasons, longer follow-up from clinical trials and those followed in the clinic will be very important for assessing the overall safety of the...

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Selzentry

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Selzentry Drug Center

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Selzentry Prescribing Information: Indications & Dosage

SELZENTRY (maraviroc) Structural Formula Illustration

SELZENTRY, in combination with other antiretroviral agents, is indicated for adult patients infected with only CCR5-tropic HIV-1.

This indication is based on analyses of plasma HIV-1 RNA levels in 2 controlled studies of SELZENTRY in treatment-experienced subjects and one study in treatment-naive subjects. Both studies in treatment-experienced subjects were conducted in clinically advanced, 3-class antiretroviral-experienced (nucleoside reverse transcriptase inhibitor [NRTI], non-nucleoside reverse transcriptase inhibitor [NNRTI], protease inhibitor [PI], or enfu...

Read the complete drug monograph for Selzentry »

What is Selzentry Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Selzentry Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using maraviroc and call your doctor at once if you have any of these serious side effects:

nausea, stomach pain, loss of appetite, skin rash, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
chest pain;
feeling like you might pass out;
sudden numbness, tingling, or weakness anywhere in your body;
cold sores, sores on your genital...

Read the complete patient information for Selzentry »

What is Selzentry Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Selzentry Consumer Information: Uses

Maraviroc, used with other medications, helps control your HIV infection, thereby improving your quality of life. It also lowers your risk of getting complications from HIV disease (e.g., new infections, cancer). Maraviroc belongs to a class of drugs known as entry inhibitors. It works by blocking the HIV virus from infecting healthy immune cells (T-cells).

This medication is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (e.g., sharing used needles).

HOW TO USE: Rea...

Read the complete consumer information for Selzentry »