Selzentry (Maraviroc) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Selzentry

HIV and AIDS: Antiretroviral Drugs, Treatments and Medications »

Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist

Entry Inhibitors
Entry inhibitors block HIV entry into CD4+ cells.

Fusion inhibitors
The only drug in this class is T-20, which is administered as a twice daily subcutaneous injection. The most common side effect is redness and pain at the site of injection. Rarely, infection can occur at the injection site. There also are reports of generalized allergic reactions.

CCR5 antagonist
Although there were some early concerns of liver inflammation for drugs in this class, MVC appeared to be well tolerated in clinical trials without any specific toxicities attributable to the drug. However, it is a new drug in a new class and the first to actually target the cell. For these reasons, longer follow-up from clinical trials and those followed in the clinic will be very important for assessing the overall safety of the...

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Selzentry

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Selzentry Patient Information Including Side Effects

Brand Names: Selzentry

Generic Name: maraviroc (Pronunciation: ma RAV i rok)

What is maraviroc (Selzentry)?

Maraviroc is an antiviral medication that prevents certain viral cells from multiplying in your body.

Maraviroc is used together with other medications. to treat CCR5-tropic human immunodeficiency virus (HIV) type 1.

Maraviroc is not a cure for HIV or AIDS.

Maraviroc may also be used for purposes not listed in this medication guide.

What are the possible side effects of maraviroc (Selzentry)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using maraviroc and call your doctor at once if you have any of these serious side effects:

nausea, stomach pain, loss of appetite, skin rash, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
chest pain;
feeling like you might pass out;
sudden numbness, tingling, or weakness anywhere in your body;
cold sores, sores on your genital or anal area;
signs of a new infection, such as fever or chills, cough, or flu symptoms.

Less serious side effects may include:

swelling;
white patches or sores inside your mouth or on your lips;
problems with urination;
runny or stuffy nose, sneezing, sore throat;
stomach pain, diarrhea;
muscle or joint pain;
dizziness; or
mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about maraviroc (Selzentry)?

Before taking this medication, tell your doctor if you have kidney disease, liver disease (especially hepatitis B or C), heart disease, low blood pressure, any type of allergy, circulation problems, or if you have ever had a stroke.

There are many other medicines that can interact with maraviroc. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

HIV/AIDS is usually treated with a combination of different drugs. Maraviroc must be given in combination with other antiviral medications. To best treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.

Taking maraviroc will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.

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