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Serax (oxazepam) is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.
Anxiety associated with depression is also responsive to Serax (oxazepam) therapy. This product has been found particularly useful in the management of anxiety, tension, agitation, and irritability in older patients.
Alcoholics with acute tremulousness, inebriation, or with anxiety associated with alcohol withdrawal are responsive to therapy.
The effectiveness of Serax (oxazepam) in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.
DOSAGE AND ADMINISTRATION
Because of the flexibility of this product and the range of emotional disturbances responsive to it, dosage should be individualized for maximum beneficial effects.
|Mild-to-moderate anxiety, with associated tension, irritability, agitation, or related symptoms of functional origin or secondary to organic disease.||10 to 15 mg, 3 or 4 times daily|
|Severe anxiety syndromes, agitation, or anxiety associated with depression.||15 to 30 mg, 3 or 4 times daily|
|Older patients with anxiety, tension, irritability, and agitation.||Initial dosage: 10 mg, 3 times daily, if necessary, increase cautiously to 15 mg, 3 or 4 times daily.|
|Alcoholics with acute inebriation, tremulousness, or anxiety on withdrawal.||15 to 30 mg, 3 or 4 times daily*|
This product is not indicated in pediatric patients under 6 years of age. Absolute dosage for pediatric patients 6 to 12 years of age is not established.
Serax (oxazepam) Capsules and Tablets are available In the following dosage strengths:
10 mg, NDC 63857-327-10, white and pink capsule marked "SERAX (oxazepam) ", "10*. and "327", in bottles of 100 capsules.
15 mg, NDC 63857-328-10, white and red capsule marked "SERAX (oxazepam) ", "15", and "328", in bottles of 100 capsules.
30 mg, NDC 63857-329-10, white and maroon capsule marked "SERAX (oxazepam) ", "30". and "329", in bottles of 100 capsules.
15 mg, NDC 63857-332-10, yellow, five-sided, flat-faced, beveled edge tablet with a raised "S* on one side and "SERAX (oxazepam) " and "15" on the other side, in bottles of 100 tablets.
Store at room temperature, approximately 25° C (77* F). Keep tightly closed. Dispense in tight container. Reference
1. FOX, KA; LAHCEN, R.8.: Liver-cell Adenomas and Poliosis Hepatis In Mice Associated with Oxazepam. Res. Commun. Chem. Pathol. Pharmacol. 8:481-488,1974.
Manufactured for Fauldino Laboratories Inc. Raleigh, NC 27608. By. Wyeth Laboratories Inc., A Wyeth-Ayerst Company Philadelphia PA 19101. Revision June 2000.
Last reviewed on RxList: 3/20/2009
This monograph has been modified to include the generic and brand name in many instances.
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