Brand Names: Seroquel, Seroquel XR

Generic Name: quetiapine (Pronunciation: kwe TYE a peen)

• What is quetiapine (Seroquel XR)?
• What are the possible side effects of quetiapine (Seroquel XR)?
• What is the most important information I should know about quetiapine (Seroquel XR)?
• What should I discuss with my healthcare provider before taking quetiapine (Seroquel XR)?
• How should I take quetiapine (Seroquel XR)?
• What happens if I miss a dose (Seroquel XR)?
• What happens if I overdose (Seroquel XR)?
• What should I avoid while taking quetiapine (Seroquel XR)?
• What other drugs will affect quetiapine (Seroquel XR)?
• Where can I get more information?

What is quetiapine (Seroquel XR)?

Quetiapine is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Quetiapine is used to treat schizophrenia in adults and children who are at least 13 years old.

Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old.

Quetiapine is also used together with antidepressant medications to treat major depressive disorder in adults.

Extended-release quetiapine (Seroquel XR) is for use only in adults and should not given to anyone younger than 18 years old.

Quetiapine may also be used for other purposes not listed in this medication guide.

Seroquel 100 mg

round, yellow, imprinted with SEROQUEL 100

Seroquel 200 mg

round, white, imprinted with SEROQUEL 200

Seroquel 25 mg

round, peach, imprinted with SEROQUEL 25

Seroquel 300 mg

oblong, white, imprinted with SEROQUEL, 300

What are the possible side effects of quetiapine (Seroquel XR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Other serious side effects include:

• fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;
• jerky muscle movements you cannot control;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance;
• fever, chills, body aches, flu symptoms;
• white patches or sores inside your mouth or on your lips;
• increased thirst, frequent urination, excessive hunger, or weakness;
• feeling like you might pass out; or
• urinating less than usual or not at all.

Less serious side effects may include:

• dizziness, drowsiness, or weakness;
• dry mouth, runny nose, sore throat;
• nausea, vomiting, stomach pain, constipation;
• blurred vision, headache, anxiety, agitation;
• breast swelling or discharge;
• missed menstrual periods; or
• weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about quetiapine (Seroquel XR)?

Quetiapine is not for use in psychotic conditions related to dementia. Quetiapine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Stop using quetiapine and call your doctor at once if you have the following symptoms: fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, uncontrolled muscle movements, symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.