June 27, 2016

Serrapeptase

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What other names is Serrapeptase known by?

Butterfly Enzyme, Enzyme de Ver de Soie, Extrait de Ver de Soie, SER, Serratia peptidase, Serrapeptidase, Serratiopeptidase, Silk Worm Enzyme, Silkworm Extract.

What is Serrapeptase?

Serrapeptase is a chemical taken from the silkworm. It is a commonly used drug (Takeda Chemical Industries) in Japan and Europe. In the U.S., serrapeptase is classified as a dietary supplement.

Serrapeptase is used for painful conditions including back pain, osteoarthritis, rheumatoid arthritis, osteoporosis, fibromyalgia, carpel tunnel syndrome, migraine headache, and tension headache.

It is also used for conditions that involve pain and swelling (inflammation) including sinusitis, laryngitis, sore throat, ear infections, swelling after surgery, swelling of a vein with the formation of a blood clot (thrombophlebitis), and inflammatory bowel disease (IBD) including ulcerative colitis and Crohn's disease.

Some people use serrapeptase for heart disease and "hardening of the arteries" (atherosclerosis).

Women use it for non-cancerous lumpy breasts (fibrocystic breast disease), and nursing mothers use it for breast pain caused by too much milk (breast engorgement).

Other uses include treatment of diabetes, leg ulcers, asthma, and pus accumulation (empyema).

Possibly Effective for...

  • Facial swelling after surgery to clear the sinuses.

Insufficient Evidence to Rate Effectiveness for...

  • Chronic bronchitis. Developing research suggests that serrapeptase can significantly reduce coughing and thin secretions in people with chronic bronchitis after about 4 weeks of treatment.
  • Sinus pain (sinusitis). Early research suggests that people with sinusitis who take serrapeptase have significantly reduced pain, nasal secretions, and nasal obstruction after 3-4 days of treatment.
  • Hoarseness (laryngitis). Early research suggests that serrapeptase can significantly reduce pain, secretions, difficulty swallowing, and fever in people with laryngitis after 3-4 days of treatment.
  • Sore throat (pharyngitis). Early research suggests that serrapeptase can significantly reduce pain, secretions, difficulty swallowing, and fever in people with sore throat after 3-4 days of treatment.
  • Back pain.
  • Osteoarthritis.
  • Rheumatoid arthritis.
  • Osteoporosis.
  • Carpel tunnel syndrome.
  • Diabetes.
  • Leg ulcers.
  • Migraine headache.
  • Tension headache.
  • Asthma.
  • Pus accumulation (empyema).
  • Thrombophlebitis.
  • Fibromyalgia.
  • Fibrocystic breast disease.
  • Inflammatory bowel disease (IBD) including ulcerative colitis and Crohn's disease.
  • Breast engorgement.
  • Heart disease.
  • Ear infections.
  • Other conditions.
More evidence is needed to rate the effectiveness of serrapeptase for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).


Therapeutic Research Faculty copyright

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