Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
What are STDs and how can their spread be prevented?
Sexually transmitted diseases (STDs) are infections that
are transmitted during any type of sexual exposure, including intercourse
(vaginal or anal), oral sex, and the sharing of sexual devices, such as
vibrators. In the professional medical arena, STDs are referred to as STIs
(sexually transmitted infections). This terminology is used because many
infections are frequently temporary. Some STDs are infections that are
transmitted by persistent and close skin-to-skin contact, including during
sexual intimacy. Although treatment exists for many STDs, others currently are
usually incurable, such as HIV, HPV, hepatitis B and C, and HHV-8.
Furthermore, many infections can be present in, and be spread by, patients who
do not have symptoms.
The most effective way to prevent the spread of STDs is abstinence.
Alternatively, the diligent use of latex barriers, such as condoms, during
vaginal or anal intercourse and oral-genital contact helps decrease the spread
of many of these infections. Still, there is no guarantee that transmission will
not occur. In fact, preventing the spread of STDs also depends upon appropriate
counseling of at-risk individuals and the early diagnosis and treatment of those
infected.
In this article, the STDs in men have been organized
into three major categories: (1) STDs that are associated with genital lesions;
(2) STDs that are associated with urethritis (inflammation of the urethra, the canal through which
urine flows out); and
(3) systemic STDs (involving various organ systems of the body). Note, however,
that some of the diseases that are listed as being associated with genital
lesions (for example, syphilis) or with urethritis (for example, gonorrhea) can also have systemic involvement.
Diseases Associated With Genital Lesions
Chancroid
What is chancroid?
Chancroid is a bacterial infection with the bacteria Hemophilus ducreyi.
The infection initialy manifests in a
sexually exposed area of the skin. The infection typically appears on the penis
but also occasionally occurs in the anal or mouth area. Chancroid starts out as a tender bump that
emerges 3 to 10 days (the incubation period)
after the sexual exposure. The bump then erupts into an ulcer (an open sore),
which is usually painful. Often, there is an associated tenderness of the glands
(lymph nodes), for example, in the
groin of patients with penile bumps or ulcers. Chancroid is a relatively rare
cause of genital lesions in the U.S., but is much more common in many developing
countries.
How is chancroid diagnosed?
The diagnosis of chancroid is usually made by a culture
of the ulcer to identify the causative bacteria. A clinical
diagnosis (which
is made from the medical history and
physical examination) can be made if the patient has one or more painful ulcers
and there is no evidence for an alternative diagnosis such as syphilis or
herpes. The clinical diagnosis
justifies the treatment of chancroid even if cultures are not available.
Incidentally, the word chancroid means resembling a "chancre," which is the
medical term for the painless genital ulcer that is seen in syphilis. Chancroid
is also sometimes called "soft chancre" to distinguish it from the chancre of
syphilis, which feels hard to the touch.
How is chancroid treated?
Chancroid is almost always cured with a single oral dose
of 1 gram of azithromycin (Zithromax) or a single injection of ceftriaxone
(Rocephin). Alternative medications are ciprofloxacin (Cipro), 500 mg taken
twice per day by mouth for three days, or erythromycin, 500 mg taken four times
per day by mouth for 7 days. Whichever treatment is used, the ulcers should
improve within 7 days. If no improvement is seen after treatment, the patient
should be reevaluated for other causes of the ulcers. HIV-infected individuals
are at an increased risk of failing treatment for chancroid. They should
therefore be followed especially closely to assure that the treatment has
worked. In addition, someone diagnosed with chancroid should be tested for other
sexually transmitted diseases (such as chlamydia and gonorrhea), because more than one
infection can be present at the same time.
What should a person do if exposed to someone with chancroid?
A health care practitioner should evaluate anyone who has had
sexual contact with a person with chancroid. Whether or not the exposed
individual has an ulcer, they should be treated if they were exposed to their
partner's ulcer. Likewise, if they had contact within 10 days of the onset of their partner's ulcer, they
should be treated even if their partner's ulcer was not present at the time of
the exposure.