Skin Problems and Treatments Resources
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The skin has an important role to play in the fluid and temperature regulation of the body. If enough skin area is injured, the ability to maintain that control can be lost. The skin also acts as a protective barrier against the bacteria and viruses that inhabit the world outside the body.
The anatomy of the skin is complex, and there are many structures within the layers of the skin. There are three layers:
The amount of damage that a burn can cause depends upon its location, its depth, and how much body surface area that it involves.
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Medical Editor: John P. Cunha, DO, FACOEP
Silvadene Cream 1% (silver sulfadiazine) is used to treat or prevent infections on areas of burned skin. It is a topical (for the skin) antibiotic. This medication is available in generic form. Common side effects include pain, burning, or itching of the treated skin. Skin and mucous membranes (such as the gums) may become blue/gray in color.
Burn areas should be covered with Silvadene Cream 1% at all times. The cream should be applied once to twice daily to a thickness of approximately 1/16 inch. Whenever necessary, the cream should be reapplied to any areas where it has been removed by patient activity. Silvadene Cream may interact with cimetidine. Tell your doctor all medications you use. During pregnancy, Silvadene Cream should be used only when prescribed. It must not be used near the expected delivery date because of possible harm to the fetus. It is unknown if this medication passes into breast milk. Similar drugs pass into breast milk and may harm nursing infants who are ill, premature, less than 2 months old, or who have certain disorders (such as jaundice, high blood levels of bilirubin, G6PD deficiency). Breast-feeding while using this drug is not recommended in infants with these conditions. Consult your doctor before breast-feeding.
Our Silvadene Cream 1% (silver sulfadiazine) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
SILVADENE Cream 1% (silver sulfadiazine) is a topical antimicrobial drug indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.
Read the complete drug monograph for Silvadene »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Read the complete patient information for Silvadene »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Silver sulfadiazine must not be used on premature babies or on newborns during the first 2 months of life because of the risk of serious side effects.
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Read the complete consumer information for Silvadene »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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