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SILVADENE® CREAM 1%
SILVADENE Cream 1% is a soft, white, water-miscible cream containing the antimicrobial agent silver sulfadiazine in micronized form, which has the following structural formula:
Each gram of SILVADENE Cream 1% contains 10 mg of micronized silver sulfadiazine. The cream vehicle consists of white petrolatum, stearyl alcohol, isopropyl myristate, sorbitan monooleate, polyoxyl 40 stearate, propylene glycol, and water, with methylparaben 0.3% as a preservative. SILVADENE Cream 1% (silver sulfadiazine) spreads easily and can be washed off readily with water.
What are the possible side effects of silver sulfadiazine topical (Silvadene, SSD, SSD AF, Thermazene)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fever, chills, body aches, flu symptoms;
- easy bruising or bleeding, unusual weakness;
- pale or yellowed skin, dark colored urine;
- ulcers on treated skin areas;
- blood in your urine;
- urinating less than usual or not at all;
- drowsiness, confusion, mood...
What are the precautions when taking silver sulfadiazine (Silvadene)?
Before using silver sulfadiazine, tell your doctor or pharmacist if you are allergic to it; or to other sulfa antibiotics (such as sulfamethoxazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain enzyme deficiency (G6PD or glucose-6-phosphate dehydrogenase deficiency), kidney problems, liver problems, low white blood cell count.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be...
Last reviewed on RxList: 3/28/2013
This monograph has been modified to include the generic and brand name in many instances.
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