In this Article

• What is niacin and simvastatin (Simcor)?
• What are the possible side effects of niacin and simvastatin (Simcor)?
• What is the most important information I should know about niacin and simvastatin (Simcor)?
• What should I discuss with my healthcare provider before taking niacin and simvastatin (Simcor)?
• How should I take niacin and simvastatin (Simcor)?
• What happens if I miss a dose (Simcor)?
• What happens if I overdose (Simcor)?
• What should I avoid while taking niacin and simvastatin (Simcor)?
• What other drugs will affect niacin and simvastatin (Simcor)?
• Where can I get more information?

What happens if I miss a dose (Simcor)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Simcor)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking niacin and simvastatin (Simcor)?

Grapefruit and grapefruit juice may interact with simvastatin and lead to potentially dangerous effects. Do not drink more than 1 quart of grapefruit juice daily.

If you also take cholestyramine (Prevalite, Questran) or colestipol (Colestid), avoid taking them within 4 to 6 hours before or after you take niacin and simvastatin.

Avoid eating foods that are high in fat or cholesterol. Niacin and simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

What other drugs will affect niacin and simvastatin (Simcor)?

Tell your doctor about all other medications you use, especially:

• colchicine (Colcrys);
• digoxin (Lanoxin);
• blood pressure medication;
• a blood thinner such as warfarin (Coumadin, Jantoven);
• other medicines that contain niacin (Advicor, Niaspan, Niacor, Slo-Niacin, and others); or
• any other "statin" medication such as atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), or simvastatin (Zocor, Vytorin).

This list is not complete and other drugs may interact with niacin and simvastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about niacin and simvastatin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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