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(acyclovir) Buccal Tablet


SITAVIG (acyclovir) buccal tablet is applied topically to the gum and releases acyclovir as the buccal tablet gradually dissolves [see CLINICAL PHARMACOLOGY].

Acyclovir is a synthetic purine nucleoside analogue active against herpes viruses. The chemical name of acyclovir is 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6Hpurin-6-one; it has a molecular formula of C8H11N5O3 and a molecular weight of 225. The structural formula is shown in Figure 1.

Figure 1: Structural Formula of Acyclovir

SITAVIG (acyclovir) Figure 1 Illustration

Acyclovir drug substance is a white or almost white crystalline powder.

SITAVIG contains 50 mg of acyclovir, USP and the following inactive ingredients: hypromellose, USP; milk protein concentrate; sodium lauryl sulfate, NF; magnesium stearate, NF; microcrystalline cellulose, NF; povidone, USP; colloidal silicon dioxide, NF.

Last reviewed on RxList: 4/29/2013
This monograph has been modified to include the generic and brand name in many instances.

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