Skelid (Tiludronate) Drug Overview and Uses for Patients and Caregivers at RxList

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May 27, 2012

Skelid

Paget's Disease »

What is Paget's disease?

Paget's disease is a chronic condition of bone characterized by disorder of the normal bone remodeling process. Normal bone has a balance of forces that act to lay down new bone and take up old bone. This relationship (referred to as "bone remodeling") is essential for maintaining the normal calcium levels in our blood. In bone affected by Paget's disease, the bone remodeling is disturbed and not synchronized. As a result, the bone that is formed is abnormal, enlarged, not as dense, brittle, and prone to breakage (fracture).

Paget's disease affects older skeletal bone of adults. It's estimated that 1% of adults in the U.S. have Paget's disease. There is also an extremely rare form of Paget's disease in children, referred to as juvenile Paget's disease. Paget's disease is also known as osteitis deformans.

What causes Paget's disease?

It is not known what causes Paget's disease. Recently, certain...

Read the Paget's Disease article »

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Skelid Consumer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

TILUDRONATE - ORAL

(till-EW-dro-nate)

COMMON BRAND NAME(S): Skelid

USES: Tiludronate is used to treat a certain type of bone disease called Paget's disease. This disease weakens and deforms bones. Tiludronate works by slowing bone loss, helping to keep your bones strong and less likely to break. It also helps reduce bone pain from this disease. This medication belongs to a class of drugs called bisphosphonates.

HOW TO USE: Follow these instructions very closely to make sure you absorb as much of the drug as possible and reduce the risk of injury to your esophagus. Consult your doctor or pharmacist if you have any questions.

Take this medication by mouth without food, usually once a day or as directed by your doctor. Take it on an empty stomach at least 2 hours before or 2 hours after a meal.

Take tiludronate with a full glass of plain water (6 to 8 ounces, 180 to 240 milliliters). Do not take it with any other beverage. After taking tiludronate, stay fully upright (sitting, standing, or walking) and do not lie down for at least 30 minutes.

Do not take tiludronate at the same time as food or other medications because they may affect its absorption. Take this medication 2 hours before or 2 hours after taking any products that contain aluminum, calcium, iron, magnesium, or zinc. Some examples include certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), quinapril, vitamins/minerals, dairy products (such as milk, yogurt), and calcium-enriched juice.

If you take antacids that contain aluminum or magnesium, take them at least 2 hours after taking tiludronate.

If you take aspirin or indomethacin, take the dose 2 hours before or 2 hours after your tiludronate dose.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day, usually for 3 months or as directed by your doctor.