July 24, 2016
Recommended Topic Related To:

Skin Exposure Paste

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Skin Exposure Paste

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Skin Exposure Paste Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 6/16/2016

Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA) contains a mixture of a perfluoroalkylpolyether (PFPE) and a polytetrafluoroethylene (PTFE) that acts as a physical barrier used only in conjunction with MOPP gear to reduce or delay the absorption of chemical warfare agents through the skin when SERPACWA is applied prior to exposure. The brand name Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA) is discontinued, but generic versions may be available. Side effects of Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA) are uncommon; consult your doctor.

Apply the SERPACWA by hand onto the skin until there is a barely noticeable white film layer. Apply the entire contents of the 84-gram package of SERPACWA evenly to the areas of the skin (as outlined in Instructions for Use for Military Personnel) prior to donning MOPP gear. SERPACWA may interact with DEET products. Tell your doctor all medications and supplements you use. During pregnancy, SERPACWA should be used only if prescribed. Consult your doctor before breastfeeding.

Our Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Skin Exposure Paste FDA Prescribing Information: Side Effects
(Adverse Reactions)


Tests conducted in humans demonstrated that topical application of SERPACWA is not associated with acute skin irritation or with allergic sensitization. Exposure of SERPACWA-treated skin to ultraviolet light was not associated with skin irritation or allergic sensitization. SERPACWA application to 20% of body surface area did not impair normal heat exchange for personnel who were exposed to an environment that simulated the effects of wearing MOPP 4 gear. In the clinical trials in which a single dose of SERPACWA was applied to humans and left in place for a five hour period, no adverse events were found to be associated with SERPACWA use.

Read the entire FDA prescribing information for Skin Exposure Paste (Perfluoroalkylpolyether (PFPE), Polytetrafluoroethylene (PTFE))

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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