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Skin Test For Allergy (cont.)

Can you give an example of a skin test?

If a specific food allergy is suspected, a skin test uses a dilute extract of the suspect food. A small drop of this particular liquid extract is placed on the skin of the forearm or back. This underlying skin is gently punctured through the small drop with a special puncture device. If the skin reddens and, more importantly, if it swells, then the test is read as positive. If there is no reaction, it is read as negative.

If the skin test is positive, it implies that the patient has a type of antibody (IgE antibody) on specialized cells in the skin that release histamine to cause redness and itching. (These cells are called mast cells and the IgE antibody bound to them is specific to the food being tested.)

What are the advantages of skin tests?

Skin tests are rapid, simple, and relatively safe. They can be very helpful in specifically identifying causes of allergies.

Is there danger to a skin test?

In some extremely allergic patients who have severe reactions called anaphylactic reactions, skin testing cannot be used because it could evoke a dangerous reaction. Skin testing also cannot be done on patients with extensive eczema.

What is done if a skin test can't be done?

For these patients a doctor may use special blood tests, such as the RAST and the ELISA. These tests measure the presence of specific types of IgE in the blood.

These tests may cost more than skin tests, and results are not available immediately. As with skin testing, positive RAST and ELISA tests do not by themselves necessarily make the final diagnosis.

Medically reviewed by Michael Manning, MD; American Board of Allergy & Immunology


"Overview of skin testing for allergic disease"

Medically Reviewed by a Doctor on 2/27/2014

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