Slo-phyllin (Theophylline, Anhydrous) Drug Information: Side Effects and Drug Interactions

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May 27, 2012

Slo-phyllin

Asthma »

Myths, facts, and statistics about asthma

Before we present the typical symptoms of asthma, we should dispel some common myths about this condition. This is best achieved by conducting a short true or false quiz.

T or F - Asthma is "all in the mind."
T or F - You will "grow out of it."
T or F - Asthma can be cured, so it is not serious and nobody dies from it.
T or F - You are likely to develop asthma if someone in your family has it.
T or F - You can "catch" asthma from someone else who has it.
T or F - Moving to a different location, such as the desert, can cure asthma.
T or F - People with asthma should not exercise.
T or F - Asthma is best controlled when one has an asthma management plan designed by your doctor. This should include the medications used for quick relief as well as maintenance therapy.
T or F - Medications used to treat asthma are habit...

Read the Asthma article »

Slo-phyllin

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

SIDE EFFECTS

The following adverse reactions have been observed, but there has not been enough systematic collection of data to support an estimate of their frequency. The most consistent adverse reactions are usually due to overdosage.

Gastrointestinal: nausea, vomiting, epigastric pain, hematemesis, diarrhea.

Central Nervous System: headaches, irritability, restlessness, insomnia, reflex hyperexcitability, muscle twitching, clonic and tonic generalized convulsions.

Cardiovascular: palpitation, tachycardia, extrasystoles, flushing, hypotension, circulatory failure, ventricular arrhythmias.

Respiratory: tachypnea.

Renal: potentiation of diuresis.

Other: alopecia, hyperglycemia, inappropriate ADH syndrome, rash.

DRUG INTERACTIONS

Drug-Drug Interactions: Toxic synergism with ephedrine has been documented and may occur with some other sympathomimetic bronchodilators. In addition, the following drug interactions have been demonstrated:

Theophylline with Drug	Effect
Allopurinol (high dose)	Increased serum theophylline levels
Cimetidine	Increased serum theophylline levels
Ciprofloxacin	Increased serum theophylline levels
Erythromycin, Troleandomycin	Increased serum theophylline levels
Lithium carbonate	Increased renal excretion of lithium
Oral contraceptives	Increased serum theophylline levels
Propranolol	Increased serum theophylline levels
Phenytoin	Decreased theophylline and phenytoin serum levels
Rifampin	Decreased serum theophylline levels