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Last reviewed on RxList: 12/8/2004
Please Note: This Brand Name drug is no longer available in the US. (Generic versions may still be available.)
Slo-phyllin Side Effects Center

Last reviewed on RxList 2/7/2016

Slo-Phyllin (theophylline tablets) is a bronchodilator used for relief and/or prevention of symptoms of asthma and reversible bronchospasm associated with chronic bronchitis and emphysema. The brand name Slo-Phyllin is discontinued, but generic versions may be available. Common side effects of Slo-Phyllin (theophylline tablets) include nausea, vomiting, abdominal discomfort, headache, insomnia, diarrhea, irritability, restlessness, muscle tremors, increased urination, decreased blood pressure, and heart palpitations.

The initial dose of Slo-Phyllin is 16 mg/kg/24 hours or 400 mg/24 hours (whichever is less) of anhydrous theophylline in divided doses at 6-or 8-hour intervals. Slo-Phyllin may interact with ephedrine, or other sympathomimetic bronchodilators. Tell your doctor all medications and supplements you use. During pregnancy, Slo-Phyllin should be used only if prescribed. This drug passes into breast milk and may cause irritability or other signs of mild toxicity in nursing infants. Consult your doctor before breastfeeding.

Our Slo-Phyllin (theophylline tablets) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Slo-phyllin Professional Information


The following adverse reactions have been observed, but there has not been enough systematic collection of data to support an estimate of their frequency. The most consistent adverse reactions are usually due to overdosage.

Gastrointestinal: nausea, vomiting, epigastric pain, hematemesis, diarrhea.

Central Nervous System: headaches, irritability, restlessness, insomnia, reflex hyperexcitability, muscle twitching, clonic and tonic generalized convulsions.

Cardiovascular: palpitation, tachycardia, extrasystoles, flushing, hypotension, circulatory failure, ventricular arrhythmias.

Respiratory: tachypnea.

Renal: potentiation of diuresis.

Other: alopecia, hyperglycemia, inappropriate ADH syndrome, rash.

Read the entire FDA prescribing information for Slo-phyllin (Theophylline, Anhydrous)

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© Slo-phyllin Patient Information is supplied by Cerner Multum, Inc. and Slo-phyllin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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