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Sodium Bicarbonate

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  • GERD is a condition in which the acidified liquid content of the stomach up into the esophagus.
  • The causes of GERD include an abnormal lower esophageal sphincter, hiatal hernia, abnormal esophageal contractions, and slow emptying of the stomach.
  • GERD may damage the lining of the esophagus, thereby causing inflammation (esophagitis), although usually it does not.
  • The symptoms of uncomplicated GERD are heartburn, regurgitation, and nausea.
  • Complications of GERD include ulcers and strictures of the esophagus, Barrett's esophagus, cough and asthma, throat and laryngeal inflammation, inflammation and infection of the lungs, and collection of fluid in the sinuses and middle ear.
  • Barrett's esophagus is a pre-cancerous condition that requires periodic endoscopic surveillance for the development of cancer.
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Sodium Bicarbonate

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5% Sodium Bicarbonate Injection, USP (sodium bicarbonate (sodium bicarbonate 5% injection) 5% injection)

DRUG DESCRIPTION

5% Sodium Bicarbonate Injection, USP (sodium bicarbonate (sodium bicarbonate 5% injection) 5% injection) is a sterile, nonpyrogenic solution of Sodium Bicarbonate (sodium bicarbonate 5% injection) , USP in Water for Injection, USP. It contains no antimicrobial agent. Composition, osmolarity, pH and ionic concentration are shown below.

  Composition   Ionic Concentration (mEq/L)
  Sodium Bicarbonate (sodium bicarbonate 5% injection) , USP
(NaHCO3) (g/L)
Osmolarity
(mOsmol/L) (calc.)
*pH Sodium Bicarbonate
5% Sodium Bicarbonate Injection, USP 50 1190 8 (7.0 to 8.5) 595 595
Approximately 0.007% edetate disodium added as a stabilizer.
*pH adjusted with carbon dioxide.

Last reviewed on RxList: 9/16/2008
This monograph has been modified to include the generic and brand name in many instances.

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